What is Klovinal: Uses, Side Effects, and Effectiveness
Klovinal is a combination medication widely used in the treatment of vaginal infections, especially those caused by a mix of bacteria and fungi. Its unique formulation makes it particularly effective for women dealing with recurring infections or symptoms that do not respond well to single-ingredient medications. This article explores what Klovinal is, its uses, potential side effects, and how effective it is in treating infections.
What Is Klovinal?
Klovinal is a vaginal suppository that contains a combination of three active ingredients:
- Clotrimazole: An antifungal agent that fights fungal infections like Candida albicans, which causes yeast infections.
- Metronidazole: An antibiotic effective against anaerobic bacteria and protozoa, often used to treat bacterial vaginosis.
- Lactobacillus spores: A probiotic that helps restore and maintain the normal vaginal flora, which is often disrupted during infections or antibiotic treatment.
This combination makes Klovinal a broad-spectrum treatment, addressing both the cause of the infection and helping to prevent recurrence.
Klovinal is typically prescribed for the treatment of:
- Bacterial vaginosis (BV)
- Vaginal candidiasis (yeast infections)
- Mixed vaginal infections (caused by both bacteria and fungi)
- Recurring vaginal infections
- Imbalance in vaginal flora (after antibiotic use or hormonal changes)
Doctors may also recommend Klovinal as part of post-infection recovery, especially after treating bacterial infections with strong antibiotics.
How to Use Klovinal
Klovinal is used intravaginally, that is, it is inserted into the vagina, usually at night, before bed. This allows the medication to stay in place and work effectively overnight. Treatment generally lasts for 6 to 7 days, but the exact duration should be determined by a healthcare provider.
Here’s a basic guide to using Klovinal:
- Wash your hands thoroughly before and after use.
- Lie on your back and gently insert the suppository into the vagina using your finger or an applicator.
- Remain lying down for a few minutes to allow the suppository to dissolve.
- Always complete the full course, even if symptoms disappear early.
- Avoid sexual intercourse during treatment, and consult your doctor if you experience any side effects or allergic reactions.

Side Effects of Klovinal
Like most medications, Klovinal can cause side effects, although not everyone will experience them. Some common and mild side effects include:
1. Vaginal irritation or itching
2. A slight burning sensation upon insertion
3. Increased vaginal discharge (as the infection clears)
4. Less common but more serious side effects include:
5. Allergic reactions (rash, itching, swelling)
6. Severe vaginal irritation or bleeding
7. Abdominal pain
If any serious symptoms occur, stop using the medication and consult a healthcare professional immediately.
Effectiveness of Klovinal
Klovinal is generally considered highly effective in treating vaginal infections, particularly mixed infections that involve both bacteria and yeast. Its triple-action formula provides both immediate relief and long-term protection by restoring the natural vaginal environment.
Several studies and clinical reports support the effectiveness of combining antifungals, antibiotics, and probiotics, making Klovinal a trusted choice for doctors treating complex or recurring infections.
Patients often report noticeable relief within the first few days of treatment, although full recovery usually takes up to a week.
Precautions and Considerations
1. Avoid sexual intercourse during treatment, as it may reduce the effectiveness of the medication or irritate the vaginal area.
2. Do not use tampons while using Klovinal; use sanitary pads instead if you are on your period.
3. Pregnant or breastfeeding women should consult a doctor before using Klovinal.
If symptoms persist after completing the course, follow up with a healthcare provider.
Most Asked Questions?
Klovinal: What It Really Does and Doesn’t Do
Klovinal is used to treat certain types of vaginal infections, particularly those caused by a mix of bacteria and fungi. However, like many medications, Klovinal is sometimes surrounded by misconceptions or misused for conditions it’s not meant to treat. Below, we are going to answer some of the common questions to help you understand what Klovinal does, and doesn’t do.
Does Klovinal Tighten the Vagina?
No, Klovinal does not tighten the vagina.
Klovinal is not designed to tighten vaginal muscles or alter the vaginal structure. Some women may feel a sense of freshness or relief after using it, especially if they had an infection, but this should not be confused with actual vaginal tightening.
Klovinal and Pregnancy: Safety and Considerations
Klovinal should only be used during pregnancy under medical supervision.
While Clotrimazole (one of its active ingredients) is considered relatively safe in pregnancy, Metronidazole and Lactobacillus spores require caution. The safety of using all three together as in Klovinal has not been fully established for pregnant women. If you’re pregnant or trying to conceive, consult your doctor before using Klovinal.
Can Klovinal Delay Your Period? What to Expect
Klovinal does not directly delay your period, but vaginal infections or stress related to infections can sometimes affect your menstrual cycle. If you experience a delayed period while using Klovinal, it’s more likely due to hormonal changes, stress, illness, or pregnancy rather than the medication itself. Always take a pregnancy test or consult a doctor if your period is significantly late.
Does Klovinal Treat UTIs? Exploring Its Effectiveness
No, Klovinal does not treat urinary tract infections (UTIs).
UTIs affect the urinary tract (bladder, urethra, kidneys), and require different antibiotics taken orally or intravenously. Klovinal is designed for vaginal infections and has no proven effect on urinary tract infections. If you have UTI symptoms such as burning during urination or frequent urges to pee, see a healthcare provider for proper treatment.
Discharge After Using Klovinal: What’s Normal and What’s Not
Increased discharge after using Klovinal is common and usually normal.
The suppository melts and releases its contents into the vagina, leading to a creamy or watery discharge. This is part of the treatment process. However, if the discharge has a foul odor, unusual color (green or gray), or is accompanied by severe itching or pain, you may need to revisit your doctor.
Possible Side Effects of Klovinal: What You Should Know
Most users tolerate Klovinal well, but possible side effects include:
- Vaginal burning or irritation
- Increased discharge
- Itching
- Mild abdominal discomfort
- Swelling or rash around the vagina
- Allergic reactions (facial swelling, breathing difficulty)
- Neurological effects (dizziness, seizures with prolonged use)
- Unusual bleeding
Always follow dosage instructions, and do not use Klovinal more frequently or longer than prescribed.
Can Klovinal Cure Gonorrhea?
Klovinal does not cure gonorrhea.
Gonorrhea is a sexually transmitted infection caused by Neisseria gonorrhoeae and requires specific antibiotics like ceftriaxone. Klovinal’s ingredients do not target this bacterium. If you suspect you have gonorrhea or any STI, get tested and treated properly at a health facility.
Does Klovinal Treat Staph Infections? A Look at Its Efficacy
Klovinal is not intended to treat Staphylococcus (staph) infections.
Staph infections, including Staphylococcus aureus, usually affect the skin, bloodstream, or other organs and require oral or intravenous antibiotics. While Metronidazole in Klovinal targets certain bacteria, it is not effective against staph. If a staph infection is suspected, seek proper medical treatment.
NaijHealth Take
Klovinal offers a comprehensive solution for treating and preventing vaginal infections, especially when caused by both fungi and bacteria. Its combination of antifungal, antibacterial, and probiotic ingredients makes it stand out from traditional single-ingredient treatments. However, as with any medication, proper usage and medical guidance are essential to ensure safety and effectiveness.
If you experience recurring infections or are unsure about your symptoms, speak with a healthcare professional to determine whether Klovinal is the right treatment for you.
Sources:
https://onehealthng.com/product/klovinal
https://rwandafda.gov.rw/wp-content/uploads/2024/08/Klovinal_Metronidazole_500_mg_Clotrimazole_100_mg%20Lactobacillus%20spores_150_million%20spores_pessaries_PIL.pdf
https://uktis.org/monographs/use-of-metronidazole-in-pregnancy/